the 2011 HBRI Winter Newsletter
HBRI Summer Internship Program
As of March 26, 2014 HBRI has made the difficult decision
that it will not be able to offer its Summer Internship
Program for 2014.
page for more information on our Summer Internship Program.
Small Molecule Makes Heart Cells Out of Stem Cells
Diego, Calif., November 14, 2012 – Researchers at the Human
BioMolecular Research Institute, Sanford-Burnham Medical Research
Institute (Sanford-Burnham), and ChemRegen, Inc. have created
a small molecule that convert stem cells to heart cells. Writing
November 6th in the Journal of Medicinal Chemistry, the team describes
how they synthesized and tested ITD-1, a man-made, drug-like chemical
that can be used to generate unlimited numbers of new heart cells
from stem cells.
“Because heart disease is the leading cause of death in
this country, we need to effectively replace lost heart muscle
cells—called cardiomyocytes,” said Mark Mercola, Ph.D.,
director of Sanford-Burnham’s Muscle Development and Regeneration
Program and co-author of the study. “Using a small molecule
to create new heart muscle cells from stem cells is very appealing.”
HERE to read the full press release.
HERE to read more about the exciting work being done by HBRI
Human BioMolecular Research Institute (HBRI) is a 501(c)3 tax-exempt
non-profit research institute doing basic research for the public
good. HBRI was founded in December of 1997. The institute is located in the heart
of biotech beach in a state-of-the-art 6,700 sq. ft. facility.
The research programs at HBRI are focused on
unlocking biological and chemical principles related to diseases
of the human brain. Included
in the areas of study are: Alzheimer’s disease and related
neurodegenerative disorders, Parkinson’s disease, ALS, depression,
neuroprotection, regenerative medicine, cardiovascular disease,
cancer, drug and alcohol abuse, pain and smoking cessation. The institute conducts fundamental
studies of central nervous system disorders and translates findings
into new drug development to address human illness. In addition, the institute promotes
scientific learning through community service and public access
by disseminating information and sharing research with collaborators,
colleagues and the public.
Brain is not the Same"